This Regulation shall enter into force on the third day following that of its publication in the Official Journal of the European Union .

This Regulation shall be binding in its entirety and directly applicable in all Member States.

Done at Brussels, 24 July 2025.

For the Commission

The President

Ursula VON DER LEYEN

( 1 ) OJ L 309, 24.11.2009, p. 1 , ELI: http://data.europa.eu/eli/reg/2009/1107/oj .

( 2 ) Commission Implementing Regulation (EU) No 200/2013 of 8 March 2013 approving the active substance ametoctradin, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 67, 9.3.2013, p. 1 , ELI: http://data.europa.eu/eli/reg_impl/2013/200/oj ).

( 3 ) Commission Directive 2008/113/EC of 8 December 2008 amending Council Directive 91/414/EEC to include several micro-organisms as active substances ( OJ L 330, 9.12.2008, p. 6 , ELI: http://data.europa.eu/eli/dir/2008/113/oj ).

( 4 ) Council Directive 91/414/EEC of 15 July 1991 concerning the placing of plant protection products on the market ( OJ L 230, 19.8.1991, p. 1 , ELI: http://data.europa.eu/eli/dir/1991/414/oj ).

( 5 ) Commission Directive 2011/6/EU of 20 January 2011 amending Council Directive 91/414/EEC to include buprofezin as active substance ( OJ L 18, 21.1.2011, p. 38 , ELI: http://data.europa.eu/eli/dir/2011/6/oj ).

( 6 ) Commission Directive 2006/39/EC of 12 April 2006 amending Council Directive 91/414/EEC to include clodinafop, pirimicarb, rimsulfuron, tolclofos-methyl and triticonazole as active substances ( OJ L 104, 13.4.2006, p. 30 , ELI: http://data.europa.eu/eli/dir/2006/39/oj ).

( 7 ) Commission Directive 2009/37/EC of 23 April 2009 amending Council Directive 91/414/EEC to include chlormequat, copper compounds, propaquizafop, quizalofop-P, teflubenzuron and zeta-cypermethrin as active substances ( OJ L 104, 24.4.2009, p. 23 , ELI: http://data.europa.eu/eli/dir/2009/37/oj ).

( 8 ) Commission Implementing Regulation (EU) 2018/1981 of 13 December 2018 renewing the approval of the active substances copper compounds, as candidates for substitution, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 317, 14.12.2018, p. 16 , ELI: http://data.europa.eu/eli/reg_impl/2018/1981/oj ).

( 9 ) Commission Implementing Regulation (EU) No 22/2013 of 15 January 2013 approving the active substance cyflumetofen, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 11, 16.1.2013, p. 8 , ELI: http://data.europa.eu/eli/reg_impl/2013/22/oj ).

( 10 ) Commission Directive 2005/53/EC of 16 September 2005 amending Council Directive 91/414/EEC to include chlorothalonil, chlorotoluron, cypermethrin, daminozide and thiophanate-methyl as active substances ( OJ L 241, 17.9.2005, p. 51 , ELI: http://data.europa.eu/eli/dir/2005/53/oj ).

( 11 ) Commission Implementing Regulation (EU) 2015/2084 of 18 November 2015 approving the active substance flupyradifurone, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 302, 19.11.2015, p. 89 , ELI: http://data.europa.eu/eli/reg_impl/2015/2084/oj ).

( 12 ) Commission Implementing Regulation (EU) No 368/2013 of 22 April 2013 approving the active substance Helicoverpa armigera nucleopolyhedrovirus , in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 111, 23.4.2013, p. 36 , ELI: http://data.europa.eu/eli/reg_impl/2013/368/oj ).

( 13 ) Commission Implementing Regulation (EU) 2015/2085 of 18 November 2015 approving the active substance mandestrobin, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 302, 19.11.2015, p. 93 , ELI: http://data.europa.eu/eli/reg_impl/2015/2085/oj ).

( 14 ) Commission Implementing Regulation (EU) No 188/2013 of 5 March 2013 approving the active substance mandipropamid, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 62, 6.3.2013, p. 13 , ELI: http://data.europa.eu/eli/reg_impl/2013/188/oj ).

( 15 ) Commission Implementing Regulation (EU) No 359/2012 of 25 April 2012 approving the active substance metam, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 114, 26.4.2012, p. 1 , ELI: http://data.europa.eu/eli/reg_impl/2012/359/oj ).

( 16 ) Commission Directive 2004/30/EC of 10 March 2004 amending Council Directive 91/414/EEC to include benzoic acid, flazasulfuron and pyraclostrobin as active substances ( OJ L 77, 13.3.2004, p. 50 , ELI: http://data.europa.eu/eli/dir/2004/30/oj ).

( 17 ) Commission Implementing Regulation (EU) 2015/2198 of 27 November 2015 approving the active substance rescalure, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 313, 28.11.2015, p. 35 , ELI: http://data.europa.eu/eli/reg_impl/2015/2198/oj ).

( 18 ) Commission Implementing Regulation (EU) No 367/2013 of 22 April 2013 approving the active substance Spodoptera littoralis nucleopolyhedrovirus , in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 111, 23.4.2013, p. 33 , ELI: http://data.europa.eu/eli/reg_impl/2013/367/oj ).

( 19 ) Commission Implementing Regulation (EU) No 917/2014 of 22 August 2014 approving the active substance Streptomyces lydicus strain WYEC 108 in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 251, 23.8.2014, p. 19 , ELI: http://data.europa.eu/eli/reg_impl/2014/917/oj ).

( 20 ) Commission Implementing Regulation (EU) No 1238/2012 of 19 December 2012 approving the active substance Trichoderma asperellum (strain T34), in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Commission Implementing Regulation (EU) No 540/2011 ( OJ L 350, 20.12.2012, p. 59 , ELI: http://data.europa.eu/eli/reg_impl/2012/1238/oj ).

( 21 ) Commission Implementing Regulation (EU) No 17/2013 of 14 January 2013 approving the active substance Trichoderma atroviride strain I-1237, in accordance with Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market, and amending the Annex to Implementing Regulation (EU) No 540/2011 ( OJ L 9, 15.1.2013, p. 5 , ELI: http://data.europa.eu/eli/reg_impl/2013/17/oj ).

( 22 ) Commission Implementing Regulation (EU) No 540/2011 of 25 May 2011 implementing Regulation (EC) No 1107/2009 of the European Parliament and of the Council as regards the list of approved active substances ( OJ L 153, 11.6.2011, p. 1 , ELI: http://data.europa.eu/eli/reg_impl/2011/540/oj ).

( 23 ) Commission Implementing Regulation (EU) 2020/2007 of 8 December 2020 amending Implementing Regulation (EU) No 540/2011 as regards the extension of the approval periods of the active substances 1-decanol, 1,4-dimethylnaphthalene, 6-benzyladenine, acequinocyl, Adoxophyes orana granulovirus, aluminium sulfate, amisulbrom, Aureobasidium pullulans (strains DSM 14940 and DSM 14941), azadirachtin, Bacillus pumilus QST 2808, benalaxyl-M, bixafen, bupirimate, Candida oleophila strain O, chlorantraniliprole, disodium phosphonate, dithianon, dodine, emamectin, flubendiamide, fluometuron, fluxapyroxad, flutriafol, hexythiazox, imazamox, ipconazole, isoxaben, L-ascorbic acid, lime sulphur, orange oil, Paecilomyces fumosoroseus strain FE 9901, pendimethalin, penflufen, penthiopyrad, potassium phosphonates, prosulfuron, Pseudomonas sp. strain DSMZ 13134, pyridalyl, pyriofenone, pyroxsulam, quinmerac, S-abscisic acid, sedaxane, sintofen, sodium silver thiosulfate, spinetoram, spirotetramat, Streptomyces lydicus strain WYEC 108, tau-fluvalinate, tebufenozide, tembotrione, thiencarbazone, valifenalate, zinc phosphide ( OJ L 414, 9.12.2020, p. 10 , ELI: http://data.europa.eu/eli/reg_impl/2020/2007/oj ).

( 24 ) Commission Implementing Regulation (EU) 2023/689 of 20 March 2023 amending Implementing Regulation (EU) No 540/2011 as regards the extension of the approval periods of the active substances Bacillus subtilis (Cohn 1872) strain QST 713, Bacillus thuringiensis subsp. Aizawai strains ABTS-1857 and GC-91, Bacillus thuringiensis subsp. Israeliensis (serotype H-14) strain AM65-52, Bacillus thuringiensis subsp. Kurstaki strains ABTS 351, PB 54, SA 11, SA12 and EG 2348, Beauveria bassiana strains ATCC 74040 and GHA, clodinafop, Cydia pomonella Granulovirus (CpGV), cyprodinil, dichlorprop-P, fenpyroximate, fosetyl, malathion, mepanipyrim, metconazole, metrafenone, pirimicarb, pyridaben, pyrimethanil, rimsulfuron, spinosad, Trichoderma asperellum (formerly T. harzianum) strains ICC012, T25 and TV1, Trichoderma atroviride (formerly T. harzianum ) strain T11, Trichoderma gamsii (formerly T. viride ) strain ICC080, Trichoderma harzianum strains T-22 and ITEM 908, triclopyr, trinexapac, triticonazole and ziram ( OJ L 91, 29.3.2023, p. 1 , ELI: http://data.europa.eu/eli/reg_impl/2023/689/oj ).

( 25 ) Commission Implementing Regulation (EU) 2023/918 of 4 May 2023 amending Implementing Regulation (EU) No 540/2011 as regards the extension of the approval periods of the active substances aclonifen, ametoctradin, beflubutamid, benthiavalicarb, boscalid, captan, clethodim, cycloxydim, cyflumetofen, dazomet, diclofop, dimethomorph, ethephon, fenazaquin, fluopicolide, fluoxastrobin, flurochloridone, folpet, formetanate, Helicoverpa armigera nucleopolyhedrovirus , hymexazol, indolylbutyric acid, mandipropamid, metalaxyl, metaldehyde, metam, metazachlor, metribuzin, milbemectin, paclobutrazol, penoxsulam, phenmedipham, pirimiphos-methyl, propamocarb, proquinazid, prothioconazole, S-metolachlor, Spodoptera littoralis nucleopolyhedrovirus , Trichoderma asperellum strain T34 and Trichoderma atroviride strain I-1237 ( OJ L 119, 5.5.2023, p. 160 , ELI: http://data.europa.eu/eli/reg_impl/2023/918/oj ).

( 26 ) Commission Implementing Regulation (EU) 2023/1757 of 11 September 2023 amending Implementing Regulation (EU) No 540/2011 as regards the extension of the approval periods of the active substances bensulfuron, chlormequat, chlorotoluron, clomazone, daminozide, deltamethrin, eugenol, fludioxonil, flufenacet, flumetralin, fosthiazate, geraniol, MCPA, MCPB, propaquizafop, prosulfocarb, quizalofop-P-ethyl, quizalofop-P-tefuryl, sodium 5-nitroguaiacolate, sodium o-nitrophenolate, sodium p-nitrophenolate, sulfuryl fluoride, tebufenpyrad, thymol, and tritosulfuron ( OJ L 224, 12.9.2023, p. 28 , ELI: http://data.europa.eu/eli/reg_impl/2023/1757/oj ).

( 27 ) Commission Implementing Regulation (EU) 2024/324 of 19 January 2024 amending Implementing Regulation (EU) No 540/2011 as regards the extension of the approval periods of the active substances benzovindiflupyr, bromuconazole, buprofezin, cyflufenamid, fluazinam, fluopyram, flutolanil, lambda-cyhalothrin, mecoprop-P, mepiquat, metsulfuron-methyl, phosphane and pyraclostrobin ( OJ L, 2024/324, 22.1.2024, ELI: http://data.europa.eu/eli/reg_impl/2024/324/oj ).

( 28 ) Commission Implementing Regulation (EU) No 844/2012 of 18 September 2012 setting out the provisions necessary for the implementation of the renewal procedure for active substances, as provided for in Regulation (EC) No 1107/2009 of the European Parliament and of the Council concerning the placing of plant protection products on the market ( OJ L 252, 19.9.2012, p. 26 , ELI: http://data.europa.eu/eli/reg_impl/2012/844/oj ).

( 29 ) Commission Implementing Regulation (EU) 2020/1740 of 20 November 2020 setting out the provisions necessary for the implementation of the renewal procedure for active substances, as provided for in Regulation (EC) No 1107/2009 of the European Parliament and of the Council, and repealing Commission Implementing Regulation (EU) No 844/2012 ( OJ L 392, 23.11.2020, p. 20 , ELI: http://data.europa.eu/eli/reg_impl/2020/1740/oj ).

COMMISSION IMPLEMENTING REGULATION (EU) 2025/1489 of 24 July 2025 amending Implementing Regulation (EU) No 540/2011 as regards the extension of the approval periods of the active substances ametoctradin, ANNEX